Try the HORNBLOWER cruise. It goes under the GG bridge and offers dinner and dancing from what I can remember.. **MOST WANTED**
UENO AF1 SZ 7-8
REEBOK X ALIFE PUMP WHITE OR GREEN SZ 7-8
AM95 3M SZ 7.5-9
ATMOS AF1 SZ 7-8
Try going to www.thespinnaker.com/ and you could follow that up with a ferry ride which would drop you off in the Fisherman's Wharf area. You could walk along the wharf and enjoy the sites and maybe get a dessert at Ghirardelli Square.
After all of that you'll be in the city and if it's clubs or lounges you're located right in the middle of it all.