I'm beginning to make this transition.
I've worked for a family-owned company since I got out of college in '03 and really love what I do.
Unfortunately, the company won't be viable in 20-25 years when everyone else retires (I'm by far the youngest person in the company) since I have no desire to deal with the day-to-day BS of running a business.
Like the person above said, just start putting your resume out there and see if it generates any interest. Talk with friends, relatives, anyone who may be able to point you in the direction of an opportunity.
In this economy, you can't over-do it when looking for a job. Good luck.