Homer Simpson did come pretty close to figuring out the mass of the Higgs Boson before scientists did
the episode "The Wizard of Evergreen Terrace," which aired on September 20, 1998. The episode has Homer realizing that his life's half over and he hasn't accomplished anything. In order to fix it, he tries to emulate his hero (for this episode) Thomas Edison.
One of the scenes in the episode has Homer working at a chalkboard with an equation trying to figure out the mass of the Higgs Boson. While Simon Singh, author The Simpsons and Their Mathematical Secrets, tells The Independent that Homer got pretty close
If you work it out, you get the mass of a Higgs boson that's only a bit larger than the nano-mass of a Higgs boson actually is. It's kind of amazing as Homer makes this prediction 14 years before it was discovered