oh yea?????? SMOKING marijuana has ZERO health effects. ZERO....OK.
Originally Posted by IcyyyESR Two3
I can't tell if you're being serious. If you are, then yes.
One is a retrospective study, which holds very little weight. Oh, and an AVERAGE of 138 joints per week? I hope you realize how absurd thatnumber is. 20 joints a day for six years.Originally Posted by AntonLaVey
[h1]Heavy pot smoking could raise risk of heart attack, stroke[/h1] [h4]Last Updated: Tuesday, May 13, 2008 | 4:51 PM ET [/h4] [h5]CBC News[/h5]
Heavy, long-term pot smoking might raise the risk stroke or heart attack, a new study found.
Researchers at the National Institutes of Health Biomedical Research Centre in Baltimore studied whether heavy, chronic smoking of marijuana changed certain blood proteins associated with heart disease and stroke.
Eighteen participants who admitted to smoking an average of 138 joints per week over an average of six years were recruited. None had major psychiatric illnesses, high blood pressure, head injuries, were HIV-positive or had alcohol or drug dependencies.
Their blood samples were taken and measured against 24 non-drug-using volunteers.
A special protein chip that can identify blood proteins was used to analyze the blood samples.
Researchers found that apolipoprotein C-III was significantly increased in chronic marijuana smokers. Blood levels of the control participants were an average of 91.2 milligrams per 100 millilitres versus 122 milligrams per 100 millilitres for the pot smokers.
The protein, which transports triglycerides in the body, is known to slow their breakdown.
Triglyceride levels were also higher in the marijuana smokers.
Triglycerides are a type of fat that circulates in the blood. High levels of triglycerides can contribute to hardening of the arteries and an increased risk of heart attack.
The researchers believe this accumulation of apolipoprotein and triglycerides could explain why marijuana users are more likely to suffer heart attacks and strokes.
The study was published Tuesday online in the journal Molecular Psychiatry.
[h2]Hippocampal Neurotoxicity of[sup]9[/sup]-Tetrahydrocannabinol[/h2]Guy Chiu-Kai Chan, Thomas R. Hinds, Soren Impey, and Daniel R. Storm
Department of Pharmacology, University of Washington, Seattle, Washington 98195
Marijuana consumption elicits diverse physiological and psychological effects in humans, including memory loss. Here we report that[sup]9[/sup]-tetrahydrocannabinol (THC), the major psychoactive component of marijuana, is toxic for hippocampal neurons. Treatment of cultured neurons or hippocampal slices with THC caused shrinkage of neuronal cell bodies and nuclei as well as genomic DNA strand breaks, hallmarks of neuronal apoptosis. Neuron death induced by THC was inhibited by nonsteroidal anti-inflammatory drugs, including indomethacin and aspirin, as well as vitamin E and other antioxidants. Furthermore, treatment of neurons with THC stimulated a significant increase in the release of arachidonic acid. We hypothesize that THC neurotoxicity is attributable to activation of the prostanoid synthesis pathway and generation of free radicals by cyclooxygenase. These data suggest that some of the memory deficits caused by cannabinoids may be caused by THC neurotoxicity.
Originally Posted by kiuyt856
^ Those test subjects smoked 19 joints a day for 6 years. Thats a lot of smoke, but still, it says they may raise the raise the risks, and in 5000 years not a single case of death due to marijuana has occurred. There still isn't any conclusive evidence for marijuana causing heart problems, because there hasn't been a case of it happening.
Are they equal amounts of the active drug? Think about this. And they don't have the same effects on the brain. Alcohol has a greater effecton coordination.
I simply posted this to refute an absurd claim that marijuana has ZERO negative effects.Originally Posted by kiuyt856
^ Those test subjects smoked 19 joints a day for 6 years. Thats a lot of smoke, but still, it says they may raise the raise the risks, and in 5000 years not a single case of death due to marijuana has occurred. There still isn't any conclusive evidence for marijuana causing heart problems, because there hasn't been a case of it happening.
One is a retrospective study, which holds very little weight. Oh, and an AVERAGE of 138 joints per week? I hope you realize how absurd that number is. 20 joints a day for six years.I don't think any more needs to be said.
The other is speaking SOLELY about THC on a molecular level and it does little to mimic reality. THC is not the only chemical in marijuana, hell it's not even the only chemical that gets you high. Nor is this experiment at all representative of the effects of smoking marijuana- it shows the extremely-short-term effects of placing THC molecules on slices of the hippocampus. Proving what, exactly? Who knows what occurs here a day after the smoking has taken place? Who knows what happens when all the other cannabinoids reach these sae receptors? Who knows exactly the effects of this THC-hyppocampal interaction? I don't, but neither do the researches.
Give me a study that shows real, macro-scale (not cell shrinkage, DNA damage, etc., I mean liver disease, cancer, etc.) health risks associated with marijuana smoking.
-THC is the main active substance in marijuana, it is what gets you high. You're gonna have to educate me on what else in weed gets you high.
-The hippocampus is responsible for memory storage....it is well documented marijuana has adverse effects on memory.
-The acting of smoking marijuana itself poses health risks
You guys are naive to think smoking weed has ZERO side effects. I will say one thing tho people drink a lot more than they smoke, alcoholis more accessible and legal. We can't tell how negative the effects of marijuana are until people start using it as often and as much as they drink.
-THC is the main active substance in marijuana, it is what gets you high. You're gonna have to educate me on what else in weed gets you high.Originally Posted by AntonLaVey
One is a retrospective study, which holds very little weight. Oh, and an AVERAGE of 138 joints per week? I hope you realize how absurd that number is. 20 joints a day for six years.I don't think any more needs to be said.
The other is speaking SOLELY about THC on a molecular level and it does little to mimic reality. THC is not the only chemical in marijuana, hell it's not even the only chemical that gets you high. Nor is this experiment at all representative of the effects of smoking marijuana- it shows the extremely-short-term effects of placing THC molecules on slices of the hippocampus. Proving what, exactly? Who knows what occurs here a day after the smoking has taken place? Who knows what happens when all the other cannabinoids reach these sae receptors? Who knows exactly the effects of this THC-hyppocampal interaction? I don't, but neither do the researches.
Give me a study that shows real, macro-scale (not cell shrinkage, DNA damage, etc., I mean liver disease, cancer, etc.) health risks associated with marijuana smoking.
you're going to have to spell like an adult before you get anyone to write a research paper for you. who the hell are you, my professor???Originally Posted by nick0lis
-THC is the main active substance in marijuana, it is what gets you high. You're gonna have to educate me on what else in weed gets you high.Originally Posted by AntonLaVey
One is a retrospective study, which holds very little weight. Oh, and an AVERAGE of 138 joints per week? I hope you realize how absurd that number is. 20 joints a day for six years.I don't think any more needs to be said.
The other is speaking SOLELY about THC on a molecular level and it does little to mimic reality. THC is not the only chemical in marijuana, hell it's not even the only chemical that gets you high. Nor is this experiment at all representative of the effects of smoking marijuana- it shows the extremely-short-term effects of placing THC molecules on slices of the hippocampus. Proving what, exactly? Who knows what occurs here a day after the smoking has taken place? Who knows what happens when all the other cannabinoids reach these sae receptors? Who knows exactly the effects of this THC-hyppocampal interaction? I don't, but neither do the researches.
Give me a study that shows real, macro-scale (not cell shrinkage, DNA damage, etc., I mean liver disease, cancer, etc.) health risks associated with marijuana smoking.
-The hippocampus is responsible for memory storage....it is well documented marijuana has adverse effects on memory.
-The acting of smoking marijuana itself poses health risks
You guys are naive to think smoking weed has ZERO side effects. I will say one thing tho people drink a lot more than they smoke, alcohol is more accessible and legal. We can't tell how negative the effects of marijuana are until people start using it as often and as much as they drink.
That makes no sense. Equal amounts of each? Effective doses of alcohol are thousands of times higher than effective doses of THC+Cannabinoids.
I'm saying this can be tested, no one has until I see this I'm still on the fence. I did research in Psychopharmacology (Alcohol/frustration induced aggression) in college and there are ways to test all of this to know for sure. The first step would be to find out what exactly thoseeffective doses are, and test equal amounts of each doses and measure the short/long-term effects.
