It plays like the more modern Resident Evil titles. Feels much more arcade-y now than RE5 honestly. Quite a few more QTEs, action scenes/sequences are more frequent.
Also feel like they're trying to implement the "OH !@#$" factor more with minor spooks/scares being more frequent as well, in addition to the darker lighting/shading in the game design.
I also got beef with the shading/lighting. It was done poorly.
Also, the initial brightness adjustment screen (when you first boot the game) [i.e. "Adjust the slider until the ___________ is barely visible."] doesn't even reflect the brightness of the gameplay at all. It's way off.
Another thumbs down: Unable to kill zombies when they're laying prone "unawaken." Terrible change to the established franchise.
Giving the benefit of the doubt to possible day 0/day 1 patches planned. Also, since I got my copy on 360, there's the chance that the 360 sku isn't as clean as the PS3 sku.